Design and evaluation of a bioadhesive film for transdermal delivery of propranolol hydrochloride

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Design and evaluation of a bioadhesive film for transdermal delivery of propranolol hydrochloride.

The objective of the study was to develop a suitable trans-dermal delivery system for propranolol hydrochloride (PPL) via employing chitosan as a film former. Drug concentration uniformity, thickness, moisture uptake capacity and skin bioadhesion of the films were characterized. The effects of chitosan and PPL concentration and different penetration enhancers on the release and permeation profi...

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ژورنال

عنوان ژورنال: Acta Pharmaceutica

سال: 2011

ISSN: 1846-9558,1330-0075

DOI: 10.2478/v10007-011-0025-3